Some patients may have leg activity, which may either keep them awake or not allow them to achieve deeper stages of sleep. The first problem is known as restless leg syndrome, which is like a tingling or uncomfortable sensation in the legs that a person feels they have to move their legs to relieve. Some people have to get out of bed and walk around to relieve this sensation.

Another problem, which may or may not be associated with restless leg syndrome, is Periodic Leg Movement in Sleep (PLMS). These events occur after sleep onset, which keeps a person from entering the deeper, more restful sleep, and may be associated with breathing events or as a separate problem. Usually, if PLMS is a result of breathing activity it can clear up as breathing events are treated. Other times, PLMS may be a separate problem, which is usually treated with medication.